You need to use some common sense. Ask these questions:
1. What stocks am I trading
2. What is my account or trade size
3. What type of order am I using
If you’re trading S&P 500 constituents and using LMT orders with a $50,000 account then slippage will never be an issue.
If you’re trading a $1m account, on Russell 3000 constituents under $5 using MKT orders, then yes, slippage will be an issue.
I would suggest that you start with the base strategy first with those questions in mind then use a common sense application of a slippage factor. As you quite, rightly state, if you overstate the slippage when it’s not warranted, then you may be throwing away a perfectly good system for the wrong reasons. Obviously slippage will also show itself in real time trading.